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Systemic Fatigue Reduction

Meaning

Systemic Fatigue Reduction is the clinical objective of decreasing pervasive, non-specific exhaustion that affects both physical and mental performance, often stemming from chronic metabolic or endocrine dysregulation. This reduction is achieved by addressing the root physiological causes of energy depletion, such as mitochondrial dysfunction, chronic low-grade inflammation, or HPA axis imbalance. Success in this area is a key clinical marker of restored vitality and functional capacity.