Systemic Dysregulation Reversal is the clinical objective of correcting widespread, interconnected functional imbalances across multiple physiological axes, such as the HPA, HPG, and metabolic systems. It moves beyond addressing single symptoms to re-establishing synchronized, adaptive physiological function throughout the body. This comprehensive correction is necessary when chronic stress has caused cross-systemic failure.
Origin
This term is constructed from systemic, relating to the whole organism, dysregulation, meaning loss of control, and reversal, the act of turning back the pathological process. It reflects a holistic approach to chronic imbalance.
Mechanism
Reversal requires identifying the primary driver of the dysregulation, often chronic sympathetic overload or profound nutrient deficiency, and applying targeted interventions. The mechanism involves sequentially restoring the integrity of the most sensitive feedback loops, allowing downstream systems to follow suit. Success is measured by the return of diurnal rhythmicity in cortisol and the normalization of hormone metabolite ratios across various tissues.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.