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Systemic Desynchrony Reversal

Meaning

Systemic Desynchrony Reversal is the clinical process of restoring the correct temporal alignment and rhythmic coherence among the body’s various interconnected biological oscillators, including the central circadian clock and peripheral tissue clocks. Desynchrony occurs when internal rhythms, such as the sleep-wake cycle, hormone secretion patterns, and metabolic activity, become misaligned with each other or with external cues like the light-dark cycle. Reversal is a critical therapeutic objective aimed at correcting this internal temporal chaos to restore robust systemic homeostasis, which is essential for metabolic health and long-term longevity.