What is the Origin of Systemic De-Aging?

The concept stems from the convergence of gerontology, genetics, and molecular biology, particularly the research into the nine hallmarks of aging, such as genomic instability and cellular senescence. The term "Systemic De-Aging" emphasizes the whole-body, multi-target approach required to address the complexity and interconnectedness of the aging process. It is a goal-oriented framework for advanced, evidence-based health interventions.

What is the Mechanism of Systemic De-Aging?

De-aging involves therapeutic interventions that target fundamental drivers of aging, including epigenetic reprogramming, senolytic therapy to clear dysfunctional senescent cells, and telomere maintenance. Hormonally, it includes restoring youthful levels and pulsatility of anabolic hormones like Growth Hormone and DHEA, which drive essential tissue repair and regeneration. The mechanism is a coordinated biological effort to restore the integrity and efficiency of the body's intrinsic repair and maintenance systems.

Systemic De-Aging ∞ Area

Systemic De-Aging

Meaning

Systemic De-Aging is a comprehensive therapeutic objective focused on reversing or significantly slowing the measurable biological processes of aging across multiple, interconnected organ systems, rather than merely treating individual age-related diseases. This process aims to restore cellular function, repair molecular damage, and improve the overall physiological capacity to that of a chronologically younger state. It represents the pinnacle of regenerative and longevity medicine, focusing on intrinsic biological rejuvenation.