Systemic Coherence Assessment is the comprehensive clinical evaluation of how harmoniously the major regulatory systems of the body, specifically the endocrine, metabolic, immune, and nervous systems, are functioning together. This assessment goes beyond isolated lab values to analyze the interconnectedness and synchronicity of these physiological axes. High coherence is indicative of robust health and resilience.
Origin
This advanced concept is rooted in systems biology and functional medicine, which views the body not as a collection of separate organs but as an integrated network. “Coherence” is a term used to describe the orderly and predictable relationship between these systems. It moves the clinical focus from single-point pathology to network dysfunction.
Mechanism
The assessment typically involves evaluating key biomarkers across multiple domains, such as the HPA axis (cortisol rhythm), the HPT axis (thyroid function), and metabolic markers (insulin sensitivity, lipid profile). Dysregulation in one area, such as chronic inflammation, inevitably reduces coherence in others, impacting hormonal balance. The goal is to identify and restore the synchronicity between these regulatory pathways.
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