The comprehensive clinical process of measuring, analyzing, and spatially or functionally correlating a broad panel of diverse biological indicators across multiple physiological systems within an individual. This mapping includes not only hormone levels but also inflammatory markers, genetic polymorphisms, metabolic intermediates, and cellular health indicators. The goal is to generate a high-resolution, integrated profile of the patient’s current biological status, revealing hidden inter-systemic dysfunctions.
Origin
This advanced diagnostic technique is a direct application of high-throughput ‘omics’ technologies—genomics, proteomics, metabolomics—to clinical practice, rooted in the principles of systems biology. The term “mapping” refers to the process of creating a visual or analytical representation of the complex interrelationships between these diverse biological data points. It is a necessary precursor to truly personalized medicine.
Mechanism
The mechanism involves the collection of a wide array of biological samples—blood, saliva, urine, and sometimes genetic material—which are then analyzed using advanced laboratory techniques. Sophisticated computational algorithms process this massive dataset to identify patterns and correlations between markers, such as the link between high cortisol and suppressed thyroid hormone conversion. This mapping provides the clinician with the precise targets for molecular-level and system-level therapeutic intervention.
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