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Systemic Biological Vulnerability

Meaning

Systemic biological vulnerability denotes an organism-wide susceptibility to disease or functional decline, rooted in the collective fragility of multiple interconnected physiological systems, including the endocrine, immune, and metabolic networks. This broad-based predisposition arises from accumulated molecular damage, chronic inflammation, or inherited genetic weaknesses that compromise the body’s overall homeostatic capacity. It is a more comprehensive assessment than single-organ risk, signifying a heightened global risk of adverse health outcomes under stress. Recognizing this state is crucial for preventative longevity planning.