What is the Origin of Systemic Biological Friction?

This is a conceptual term that borrows the mechanical principle of 'Friction' to describe the energetic and functional cost of sub-optimal biology. In the domain of hormonal health, it provides a tangible way to discuss the energy drain and performance drag caused by chronic, unaddressed physiological imbalances. The clinical goal is to reduce this friction to enhance biological efficiency.

What is the Mechanism of Systemic Biological Friction?

The primary drivers of biological friction include chronic, low-level elevations of inflammatory cytokines, which interfere with insulin and hormone receptor function, and mitochondrial inefficiency, which increases the production of reactive oxygen species. Hormonal dysregulation, such as persistent hypercortisolemia or thyroid insufficiency, directly contributes by disrupting the delicate balance of energy allocation and repair. Reducing this friction requires interventions that restore metabolic and endocrine sensitivity.

Systemic Biological Friction

Meaning

Systemic Biological Friction is a clinical metaphor describing the cumulative, measurable inefficiency and resistance encountered within the body’s physiological processes, often manifesting as chronic low-grade inflammation, impaired cellular signaling, and reduced metabolic flexibility. This friction increases with age and chronic stress, requiring more energy to maintain basic function and accelerating overall systemic degradation. It is a key factor in the loss of vitality.