Skip to main content

Systemic Biological Adaptation

Meaning

Systemic Biological Adaptation is the comprehensive, coordinated response of multiple organ systems and regulatory pathways within the body to a sustained internal or external stressor or stimulus, leading to a new, stable physiological state. This concept is central to hormonal health, as the endocrine system constantly modulates its output to achieve allostasis, the process of achieving stability through change. Examples include the body’s long-term adjustments to chronic caloric restriction, sustained exercise, or therapeutic hormone modulation.