Systemic Anti-Aging Medicine is a specialized, integrative clinical discipline focused on the proactive detection, prevention, and reversal of age-related functional decline and chronic disease by addressing the root biological mechanisms of aging across all organ systems. This approach utilizes advanced diagnostics and personalized therapeutic strategies to optimize hormonal balance, cellular health, and genetic expression. The core objective is to extend the healthspan, the period of life lived in good health.
Origin
The phrase is derived from “systemic,” indicating a whole-body, comprehensive approach, and “anti-aging medicine,” a field that has evolved from hormone replacement to a broader focus on geroscience. It represents a clinical paradigm that views aging not as an inevitability but as a treatable condition driven by specific biological pathways.
Mechanism
Practice involves comprehensive hormonal testing and optimization, aggressive management of chronic inflammation (inflammaging), enhancement of cellular energy production (mitochondrial health), and telomere maintenance. The interventions often combine pharmaceutical-grade supplements, bioidentical hormones, personalized nutrition, and advanced lifestyle protocols to ensure coordinated, positive change across the entire physiological network.
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