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System-Wide Integration

Meaning

System-Wide Integration is the clinical and physiological concept emphasizing the interconnectedness and co-dependence of all major regulatory networks within the human body, including the endocrine, nervous, immune, and metabolic systems. In the context of health and longevity, this term signifies that optimal function in one system relies on the balanced operation of all others. Therapeutic strategies based on this principle focus on interventions that produce synergistic, broad-spectrum benefits across multiple axes, rather than isolated effects.