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System Problem

Meaning

This clinical designation refers to a complex health issue or chronic, pervasive symptom presentation that does not stem from a single, isolated organ pathology but rather from a fundamental dysregulation across multiple, interconnected physiological systems, such as the endocrine, metabolic, immune, or neurological networks. A system problem necessitates a holistic, integrated, and comprehensive approach for effective resolution, moving decisively beyond single-point treatment protocols.