What is the Origin of System Performance Metrics?

This concept is an adaptation of engineering and computational science principles applied to human physiology, emphasizing measurable output and efficiency. It moves clinical assessment from merely identifying pathology to quantifying wellness and functional capacity. The selection of these metrics is guided by their proven correlation with biological age, longevity, and overall quality of life.

What is the Mechanism of System Performance Metrics?

These metrics reflect the coordinated function of multiple organ systems, which is largely orchestrated by the endocrine and autonomic nervous systems. For example, heart rate variability reflects autonomic balance, which is modulated by cortisol and catecholamines. Metabolic flexibility is an index of hormonal signaling efficiency, particularly insulin and glucagon. By tracking these integrated outputs, clinicians can precisely evaluate the success of interventions aimed at optimizing the body's overall systemic resilience.

System Performance Metrics

Meaning

System Performance Metrics are quantifiable, clinically relevant indicators used to assess the functional output and efficiency of integrated physiological systems, extending beyond standard disease markers. These metrics include, but are not limited to, heart rate variability, metabolic flexibility, peak oxygen uptake, and cognitive processing speed. They provide a high-resolution view of the body’s homeostatic reserve and overall vitality set point.