The overarching regulatory commands, often originating from the central nervous system or the endocrine feedback loops, that dictate the functional set points and operational parameters for major physiological systems, including metabolism, stress response, and reproduction. These directives ensure systemic coordination toward maintaining internal milieu stability (homeostasis). We interpret these commands as the body’s fundamental operating instructions. Understanding these directives reveals underlying systemic priorities.
Origin
This is a conceptual term derived from control theory and systems biology applied to human physiology. ‘Directives’ signifies top-down, non-negotiable instructions that govern the behavior of subordinate subsystems.
Mechanism
System directives are executed through the coordinated release of trophic hormones (like TSH or ACTH) or direct autonomic outflow, which then cascade to effector cells via specific receptor binding. For instance, the directive for metabolic adaptation triggers changes in insulin sensitivity and substrate oxidation rates across the liver and muscle. These instructions are constantly being updated based on afferent physiological and environmental data inputs.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.