The overarching clinical discipline focused on monitoring, assessing, and modulating the primary feedback loops that govern physiological stability across multiple organ systems. This involves managing the complex interplay between the nervous, immune, and endocrine systems to maintain dynamic equilibrium. It is the governance of internal regulatory architecture.
Origin
This term reflects an integrated systems biology approach, moving beyond single-organ focus to manage interconnected regulatory networks. The management aspect implies active intervention based on systemic data interpretation.
Mechanism
Management operates by ensuring the fidelity of hypothalamic-pituitary axes and modulating downstream effector organ responses to maintain set points for critical variables like blood glucose and hormone titers. This often requires addressing synergistic inputs, such as synchronizing circadian rhythms with nutrient timing to optimize receptor responsiveness. Effective control minimizes entropic drift across the physiological landscape.
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