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Synaptic Signaling Fidelity

Meaning

Synaptic signaling fidelity refers to the accuracy, speed, and reliability of chemical and electrical communication across the synaptic cleft, the microscopic junction between two nerve cells. High fidelity ensures that the neurotransmitter message is released precisely, binds specifically to its target receptor, and is cleared efficiently, leading to a correct and robust post-synaptic response. This fidelity is essential for rapid learning, accurate memory formation, and efficient cognitive processing.