Skip to main content

Synaptic Plasticity Upregulation

Meaning

Synaptic Plasticity Upregulation describes the process where the strength and efficiency of communication between neurons are enhanced, often involving an increase in the number or functional capacity of synaptic connections, frequently driven by hormonal signals. This cellular mechanism is the biological substrate for learning, memory consolidation, and adaptation within the central nervous system, which is highly dependent on the neuroendocrine milieu. Specifically, increased receptor expression or augmented post-synaptic response contributes to this enhanced signaling capability. This up-regulation is vital for cognitive maintenance across the lifespan.