Interventions designed to increase the adaptability of neuronal connections, facilitating learning, memory consolidation, and cognitive reserve maintenance. This process is fundamental to neurobiological health across the lifespan. It represents the brain’s capacity for structural remodeling. Promoting plasticity supports cognitive longevity.
Origin
This term is fundamental to neuroscience, describing the brain’s ability to reorganize its synaptic connections in response to experience. It reflects the structural basis of memory and skill acquisition. The promotion aspect implies active facilitation of this natural process.
Mechanism
Promotion involves increasing brain-derived neurotrophic factor (BDNF) expression, often via targeted physical or cognitive challenges, which supports long-term potentiation and strengthens relevant neural circuits. Exercise, particularly aerobic activity, is a potent modulator of BDNF release in the hippocampus. Hormonal signaling, including estrogenic effects, also influences receptor density.
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