Synaptic Plasticity Improvement refers to the enhancement of the brain’s capacity to strengthen or weaken synaptic connections in response to activity, which is the cellular basis for learning and memory. This function is highly dependent on the availability of neurotrophic factors and specific neurosteroids within the central nervous system environment. Optimal plasticity is a marker of a well-supported neural network.
Origin
This term is drawn directly from molecular neuroscience, focusing on long-term potentiation and depression mechanisms. Its relevance to hormonal health arises because systemic factors, especially endocrine hormones, profoundly influence the molecular machinery governing synapse remodeling. Improvement implies actively supporting this inherent adaptability.
Mechanism
Improvement is often facilitated by increasing BDNF signaling, which promotes the growth and maintenance of dendritic spines, thereby increasing synaptic efficacy. Furthermore, the presence of specific neurosteroids can modulate GABAergic and glutamatergic transmission, allowing for more efficient encoding of new information. Hormonal balance ensures the necessary metabolic energy is available to support the high energetic cost of synaptic remodeling.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.