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Symptom Validation Science

Meaning

Symptom Validation Science is the clinical and scientific process of objectively correlating a patient’s reported subjective symptoms with measurable, underlying physiological and biochemical markers of dysfunction. This discipline seeks to bridge the gap between a patient’s lived experience of ill-health and the empirical data from laboratory and diagnostic testing. It is particularly crucial in hormonal health, where non-specific symptoms like fatigue, mood changes, and sleep disturbances often precede frank pathology and may not be captured by standard reference range testing. Successful validation allows for targeted, precision interventions.