A sustained state of hyperarousal and excessive activity in the sympathetic branch of the autonomic nervous system, leading to a chronic “fight-or-flight” physiological response. Clinically, this manifests as elevated resting heart rate, increased muscle tension, disrupted sleep architecture, and chronic suppression of parasympathetic tone. This condition reflects a state of high allostatic load, driving systemic inflammation, hormonal dysregulation, and ultimately accelerating physiological wear and tear.
Origin
The term “Sympathetic” refers to the sympathetic nervous system, and “Overload” describes an excessive, burdensome state. It is a concept derived from stress physiology and cardiology, where chronic stress is known to dysregulate autonomic balance. It is a critical diagnostic consideration in modern wellness, linking chronic lifestyle stress to measurable physiological pathology.
Mechanism
Sympathetic overload is triggered by chronic psychological or physiological stressors that continuously activate the Hypothalamic-Pituitary-Adrenal (HPA) axis and the adrenal medulla. This persistent activation leads to the excessive and sustained release of catecholamines, such as norepinephrine and epinephrine. The mechanism disrupts normal homeostasis by diverting energy from restorative processes like digestion and immune surveillance, favoring a catabolic state that depletes physiological reserves and reduces heart rate variability.
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