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Sympathetic Dominance Markers

Meaning

Sympathetic dominance markers are a set of quantifiable physiological and biochemical indicators that collectively signal a sustained state of hyperarousal and chronic activation of the sympathetic nervous system (SNS). This dominance reflects a persistent “fight-or-flight” state, indicating an imbalance in the autonomic nervous system (ANS) that compromises the body’s ability to rest and repair. Key markers include a low heart rate variability (HRV), an elevated resting heart rate, and an altered catecholamine-to-cortisol ratio. Clinically, these markers are crucial for diagnosing allostatic overload and stress-related hormonal dysregulation.