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Sustained Wakefulness Chemistry

Meaning

Sustained wakefulness chemistry refers to the optimal, regulated balance of neurochemicals and hormones that maintain an alert, conscious, and cognitively engaged state throughout the diurnal cycle. This physiological state is characterized by the appropriate temporal release of alerting neurotransmitters and the suppression of sleep-promoting signals during the day. Disruption of this chemistry, often due to poor sleep or circadian misalignment, leads to daytime fatigue and compromised cognitive function.