A set of advanced, objective, and longitudinal physiological measurements that collectively indicate an individual’s long-term capacity for robust health, energy, and resilience, moving beyond traditional disease markers. These metrics include, but are not limited to, heart rate variability (HRV), telomere length, mitochondrial function, and key anabolic-to-catabolic hormone ratios. They serve as quantifiable indicators of biological age and the efficacy of anti-aging and wellness interventions.
Origin
This is a contemporary clinical term that combines ‘sustained vitality,’ emphasizing long-term health and energetic capacity, with ‘metrics,’ the scientific term for a standard of measurement. The concept is a cornerstone of longevity and precision medicine, focusing on tracking the underlying biological determinants of healthspan rather than just the onset of pathology.
Mechanism
The metrics track the functional status of core biological systems that govern longevity and energy production. For example, maintaining a high HRV indicates a well-regulated autonomic nervous system, a key aspect of resilience. Favorable anabolic-to-catabolic ratios, such as testosterone-to-cortisol, reflect a net-positive metabolic state conducive to tissue repair and maintenance. The collective optimization of these metrics signifies a robust and well-maintained physiological reserve.
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