The long-term clinical objective of preserving high levels of systemic energy, mental acuity, and physical capacity across the lifespan by ensuring continuous, robust endocrine function and cellular energy production. This is the goal of achieving a resilient, non-senescent physiological state. It requires proactive, rather than reactive, management.
Origin
This concept is derived from longevity science and functional endocrinology, focusing on maintaining the functional output of the body’s core systems indefinitely. ‘Maintenance’ emphasizes ongoing stewardship against the natural trajectory of decline.
Mechanism
Maintenance relies on the consistent support of the HPA and HPT axes to prevent chronic fatigue and metabolic slowdown. Furthermore, it requires ongoing support for mitochondrial respiration to ensure ATP supply meets the demands of an active physiology. Regular monitoring of key biomarkers confirms the system remains within the optimal functional range, preventing the erosion of vigor over time.
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