The Sustained Vigor Index is a composite, clinical metric that quantifies an individual’s enduring capacity for high-level physical and cognitive energy, emotional resilience, and overall vitality over prolonged periods. This index moves beyond momentary performance to assess the underlying robustness of the neuroendocrine and metabolic systems that support long-term, consistent output. It is a critical indicator of hormonal balance, mitochondrial health, and the absence of chronic fatigue or systemic inflammation. A high index reflects optimal healthspan.
Origin
This is a conceptual term developed in the wellness and longevity space, combining ‘sustained’ to denote duration and consistency, with ‘vigor’ to describe the quality of life and energy. The ‘index’ suggests a measurable, multi-factorial assessment derived from various physiological and psychological markers. It is a functional endpoint for all optimization strategies, reflecting the integrated success of hormonal and metabolic management.
Mechanism
The index is mechanistically dependent on the efficient regulation of the hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-thyroid (HPT) axes, which govern stress response and metabolic rate. Optimal mitochondrial function ensures efficient ATP production for cellular energy. The neurochemical balance of dopamine and norepinephrine supports sustained cognitive drive and motivation. A high Sustained Vigor Index is maintained by a low allostatic load and a consistently favorable anabolic-to-catabolic hormonal environment.
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