Skip to main content

Sustained Therapeutic Levels

Meaning

The clinical objective of maintaining the concentration of a therapeutic agent within the systemic plasma continuously above the minimum effective concentration (MEC) for a prolonged duration. This sustained presence ensures a consistent and uninterrupted biological effect, which is particularly vital for hormonal therapies where stable signaling is necessary for long-term homeostatic regulation and clinical stability. It represents a hallmark of effective chronic drug administration and controlled-release technology.