The state of maintaining optimal physical energy, cognitive function, emotional resilience, and robust systemic health well into advanced chronological age. This term represents a comprehensive clinical outcome that extends beyond mere absence of disease to encompass a high quality of life and functional independence. Achieving this state requires the continuous optimization of hormonal, metabolic, and cellular processes.
Origin
This is a key concept in the modern longevity and anti-aging movement, moving past the historical focus on simply extending lifespan to prioritizing “healthspan.” The word “Sustained” emphasizes the long-term, continuous nature of this high-level well-being, suggesting a proactive and adaptive approach to aging. It is the ultimate goal of preventative and restorative medicine.
Mechanism
Sustained vitality is supported by a robust homeostatic mechanism, where all physiological systems operate efficiently with high reserve capacity. The underlying mechanism involves maintaining youthful hormone signaling, optimizing mitochondrial function for energy production, minimizing chronic inflammation, and preserving telomere length and genomic stability. This holistic balance allows the body to effectively adapt to environmental and metabolic stressors over decades.
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