A continuous and stable supply of metabolic fuel, typically derived from the efficient oxidation of fatty acids and glucose, that is readily available to support prolonged physical and cognitive function without the pronounced peaks and troughs associated with reliance on simple carbohydrates. Achieving this state, often through enhanced metabolic flexibility, is crucial for consistent energy levels and hormonal stability. It is the hallmark of an optimized metabolic system.
Origin
This concept originates from exercise physiology, clinical nutrition, and metabolic science, contrasting with the acute energy provided by high-glycemic foods. The term emphasizes the quality and consistency of fuel delivery, linking directly to mitochondrial health and insulin sensitivity. Clinical strategies aim to promote the body’s capacity for fat oxidation.
Mechanism
The body achieves a sustained energy substrate by efficiently shuttling fatty acids into the mitochondria for beta-oxidation, while maintaining tight glucose control to prevent insulin spikes and subsequent energy crashes. Hormones like glucagon and cortisol play roles in mobilizing stored energy, but metabolic flexibility is key, allowing cells to seamlessly switch between fuel sources. A well-tuned system ensures that the brain and muscles have a constant, reliable source of ATP production.
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