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Sustained Efficacy

Meaning

Sustained Efficacy describes the maintenance of a desired physiological response or therapeutic benefit from an endocrine intervention over an extended period without significant attenuation or the need for frequent dose escalation. In managing chronic conditions like hypothyroidism or testosterone deficiency, sustained efficacy indicates stable receptor engagement and consistent downstream signaling. We aim for this stability because intermittent or waning effects compromise long-term wellness outcomes and patient adherence to treatment protocols. This concept is the measure of long-term therapeutic success.