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Substrate Utilization Tuning

Meaning

Substrate Utilization Tuning refers to the precise clinical manipulation of dietary intake and metabolic factors to optimize the body’s preference for burning specific fuel sources, such as glucose or fatty acids, for energy production. This tuning aims to enhance metabolic flexibility, which is the capacity to seamlessly switch between substrates in response to nutrient availability and energy demand. Optimal substrate utilization is a hallmark of metabolic health and efficient hormonal signaling.