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Substrate Utilization Mastery

Meaning

Substrate Utilization Mastery refers to the advanced physiological capacity to efficiently switch between different energy sources, primarily glucose and fatty acids, in response to metabolic demand and availability. This mastery, often termed metabolic flexibility, is a hallmark of optimal endocrine and mitochondrial function, ensuring stable energy supply and preventing the accumulation of metabolic waste products. Individuals with high mastery exhibit superior body composition, sustained energy levels, and reduced risk of insulin resistance. It is a critical metric for assessing true metabolic health.