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Substrate Oxidation Optimization

Meaning

Substrate Oxidation Optimization is a metabolic objective focused on enhancing the body’s capacity to efficiently utilize the preferred energy source, whether it be glucose, fatty acids, or ketones, in response to physiological demand. This optimization is synonymous with achieving high metabolic flexibility, allowing for a seamless and rapid transition between different fuel sources without generating excessive metabolic byproducts or oxidative stress. It is a critical component of energy homeostasis and systemic resilience.