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Suboptimal Signaling Correction

Meaning

The clinical process of identifying and therapeutically addressing inefficiencies or dysfunctions in the molecular communication pathways that hormones and neurotransmitters use to transmit information to target cells. This correction moves beyond simply adjusting circulating hormone levels to focus on improving receptor sensitivity, post-receptor transduction, and gene expression fidelity. Suboptimal signaling is a common cause of persistent symptoms despite seemingly normal lab values.