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Subclinical Thyroid

Meaning

Subclinical Thyroid refers to a common biochemical state where circulating thyroid hormone levels, specifically free thyroxine (FT4) and free triiodothyronine (FT3), remain within the statistically normal laboratory reference range, yet the pituitary-derived Thyroid-Stimulating Hormone (TSH) is mildly but consistently elevated or suppressed. This condition indicates a subtle, often asymptomatic, dysfunction in the hypothalamic-pituitary-thyroid (HPT) axis feedback loop. Clinical attention to this state is crucial as it can subtly impact metabolism, energy levels, mood, and overall hormonal equilibrium before overt disease manifests.