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Structural Tissue Accrual

Meaning

Structural Tissue Accrual describes the net positive synthesis and deposition of new cellular and extracellular matrix components, specifically within load-bearing and metabolically active tissues such as skeletal muscle and bone. This anabolic process is essential for maintaining physical resilience, preventing fragility, and supporting robust metabolic health throughout the lifespan. It represents a direct and necessary physiological counterpoint to the continuous, age-related catabolism and breakdown of these tissues. Optimal hormonal signaling, particularly by Growth Hormone, IGF-1, and sex steroids, is a prerequisite for sustained, healthy accrual.