Skip to main content

Structural Scaffolding

Meaning

The complex, non-cellular extracellular matrix (ECM) composed primarily of fibrous proteins like collagen and elastin, along with ground substances such as hyaluronic acid and proteoglycans, that provides physical support, tensile strength, and organization to all tissues and organs. This scaffolding is crucial for cell adhesion, migration, and the transmission of mechanical and biochemical signals. Maintaining its integrity is paramount for tissue function and youthful form.