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Stress System Recalibration

Meaning

Stress System Recalibration refers to a targeted therapeutic process aimed at restoring the optimal functional balance and sensitivity of the neuroendocrine systems responsible for the stress response, primarily the Hypothalamic-Pituitary-Adrenal (HPA) axis. This clinical goal involves a systematic intervention to correct chronic dysregulation, shifting the system’s set point from a state of hyper- or hypo-arousal back to a state of dynamic, healthy responsiveness. Recalibration is essential for long-term hormonal health and mitigating stress-induced pathology.