Stress Susceptibility Reduction is the clinical goal of decreasing an individual’s physiological and psychological vulnerability to adverse reactions following exposure to stressors, whether acute or chronic. This involves bolstering the resilience of the HPA axis and improving the speed of autonomic recovery. Reducing susceptibility lessens the cumulative allostatic load placed upon the endocrine and metabolic systems.
Origin
‘Susceptibility’ denotes the predisposition to be affected negatively, while ‘Reduction’ indicates the active lowering of this state. This concept is central to preventative endocrinology and stress physiology, focusing on enhancing inherent coping mechanisms.
Mechanism
Reduction is achieved by optimizing the feedback sensitivity of the HPA axis, ensuring cortisol release is proportional to the stressor’s magnitude and resolves quickly. Simultaneously, training autonomic flexibility enhances vagal tone, providing a rapid counter-regulatory brake against excessive sympathetic activation. These adaptations stabilize metabolic function and protect against stress-induced endocrine imbalance.
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