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Stress Signal Transduction

Meaning

The entire, highly conserved cellular and molecular sequence of events by which a physical, emotional, or metabolic stressor is detected, converted into a specific biochemical signal, and then propagated throughout the cell and the organism to trigger an adaptive physiological response. This process is fundamental to the body’s capacity to maintain allostasis and survive challenging environmental conditions. Understanding this transduction is the primary clinical leverage point for modulating the stress response.