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Stress Response Genetics

Meaning

Stress Response Genetics is the study of inherited genetic variations that influence an individual’s physiological and hormonal reaction to psychological, environmental, and physical stressors. This domain investigates polymorphisms in genes that regulate the Hypothalamic-Pituitary-Adrenal (HPA) axis, neurotransmitter metabolism, and inflammatory pathways, which collectively determine one’s stress resilience and recovery capacity. Understanding an individual’s stress response genotype allows for the development of personalized interventions, such as specific adaptogens or behavioral modifications, to mitigate the detrimental long-term effects of chronic stress on hormonal balance and overall health.