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Stress Resilience Neurobiology

Meaning

This is the study and clinical application of the neurobiological systems, including the prefrontal cortex, amygdala, and the HPA axis, that determine an individual’s capacity to adapt, recover, and maintain functional stability in the face of chronic or acute psychological and physiological stress. Resilience is not merely the absence of stress but the efficiency of the biological machinery that manages allostatic load and rapidly restores neuroendocrine homeostasis. The clinical goal is to modulate the neural circuits and hormonal feedback loops to increase this adaptive capacity. This field emphasizes that true resilience is a measurable biological trait.