Stress Management Hormones refers to the specific endocrine signaling molecules that the body utilizes to initiate, regulate, and terminate the physiological response to acute or chronic stressors. The primary hormones in this category include cortisol, the catecholamines (epinephrine and norepinephrine), and dehydroepiandrosterone (DHEA), which together form the critical components of the body’s allostatic load system. Their balanced function is essential for adaptation and survival.
Origin
This concept is foundational to endocrinology and the study of the stress response, dating back to Hans Selye’s work on the General Adaptation Syndrome. The term emphasizes the hormones’ role as active regulators of stress rather than merely indicators of it. Clinical practice focuses on the HPA axis, which governs the release of these critical molecules.
Mechanism
The mechanism begins with the hypothalamus releasing corticotropin-releasing hormone (CRH), which signals the pituitary to release adrenocorticotropic hormone (ACTH), ultimately prompting the adrenal glands to synthesize and release cortisol and catecholamines. Cortisol mobilizes energy stores and suppresses non-essential functions like the immune response, while catecholamines drive the immediate “fight-or-flight” response. DHEA acts as a counter-regulatory, neuroprotective steroid, helping to balance the catabolic effects of prolonged cortisol exposure.
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