Stress Induced Nutrient Partitioning is the involuntary, hormonally driven redistribution of energy substrates and nutrients away from anabolic (building) processes like muscle repair and toward catabolic (breaking down) and visceral fat storage, as a direct consequence of chronic stress. This physiological shift is mediated by sustained elevation of stress hormones, which fundamentally alters the body’s energy allocation priorities. It is a significant factor in the development of central adiposity and the loss of lean muscle mass.
Origin
This clinical term combines the etiological trigger, stress, with the metabolic concept of nutrient partitioning (the differential routing of ingested nutrients to various tissues). It highlights the profound impact of chronic stress on body composition and energy distribution.
Mechanism
Elevated cortisol preferentially promotes the deposition of fat in the visceral (abdominal) depots by increasing the activity of lipoprotein lipase in these specific adipocytes. Simultaneously, cortisol inhibits protein synthesis and promotes protein breakdown in skeletal muscle to provide amino acids for hepatic gluconeogenesis, ensuring a steady supply of glucose. This dual action effectively partitions energy away from muscle maintenance and towards central fat storage.
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