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Stress-Induced Fatigue Mitigation

Meaning

Stress-Induced Fatigue Mitigation is the clinical and behavioral process of reducing the profound, persistent exhaustion that arises from chronic activation and eventual dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. This fatigue is a key symptom of allostatic overload, where the body’s resources are depleted from sustained exposure to physiological and psychological stressors. Mitigation strategies focus on restoring HPA axis rhythmicity and enhancing cellular energy production.