A precisely formulated, multi-component regimen of nutritional compounds, nutraceuticals, or biochemical precursors designed to synergistically target specific endocrine or metabolic deficiencies or enhance defined physiological pathways. The strategy involves sequencing and combining ingredients based on known interactions to achieve a greater effect than any single agent alone. This is the rational design of nutritional support.
Origin
This term arises from functional medicine and advanced nutritional science, where the empirical combination of supplements is refined through clinical observation and mechanistic understanding of nutrient-hormone interactions. “Strategic” implies a goal-oriented design based on diagnostic findings.
Mechanism
The mechanism relies on achieving synergy; for example, one component might support the synthesis of a required hormone, while another enhances the receptor sensitivity to that hormone, or a third might mitigate the negative feedback loop associated with its excess. Such stacks aim to provide necessary substrates and cofactors for optimal enzymatic reactions within endocrine glands or target tissues.
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