What is the Origin of Strategic Life Extension?

This concept emerges from the intersection of gerontology, anti-aging medicine, and systems biology, moving the focus from treating disease to extending the period of high-quality life. "Strategic" emphasizes the planned, systematic, and targeted nature of the interventions based on scientific understanding of the aging process. The goal is to compress the period of morbidity at the end of life.

What is the Mechanism of Strategic Life Extension?

The strategy operates by intervening in core biological pathways linked to senescence, including enhancing autophagy to clear damaged cellular components and stabilizing telomere length. Furthermore, it involves modulating nutrient-sensing pathways like mTOR and AMPK. Hormonal optimization plays a critical role by restoring youthful signaling patterns that support tissue repair and reduce chronic, low-grade inflammation, thereby counteracting age-related physiological decline.

Strategic Life Extension

Meaning

Strategic Life Extension is a comprehensive, multi-modal, and evidence-based approach to increasing human healthspan and lifespan by systematically targeting the known biological hallmarks of aging. This strategy integrates advanced clinical interventions, pharmacological agents, nutritional protocols, and lifestyle modifications to slow the rate of cellular and systemic decline. It is a proactive, scientific pursuit of maximal longevity and sustained vitality in a high-functioning state.