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Stimulus-Secretion Coupling

Meaning

Stimulus-secretion coupling is a fundamental, essential physiological process that meticulously describes the entire sequence of intracellular events linking the arrival of an external stimulus at an endocrine or secretory cell to the subsequent, precise release of a stored hormone or neurotransmitter. This intricate coupling mechanism forms the bedrock of rapid, highly regulated hormonal release in direct response to immediate systemic needs or acute environmental changes. It is a core principle of neuroendocrinology.