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Steroid Hormone Feedback

Meaning

Steroid Hormone Feedback refers to the fundamental physiological regulatory mechanism by which the circulating concentrations of steroid hormones, such as cortisol, testosterone, and estrogen, actively modulate their own production. This essential negative feedback loop operates primarily at the level of the hypothalamus and pituitary gland, ensuring the maintenance of hormonal homeostasis by preventing excessive or insufficient secretion. Clinical assessment of this feedback is a core method for diagnosing and managing a wide range of endocrine dysfunctions.