The therapeutic process of restoring the quantity, quality, and functional capacity of the body’s resident tissue-specific stem cell populations. This regeneration is vital for maintaining tissue homeostasis, repair, and organ reserve, as the number and potency of these progenitor cells naturally decline with age. It is a fundamental strategy for enhancing the body’s intrinsic ability to heal and renew itself.
Origin
This concept is derived from regenerative medicine and hematopoiesis, recognizing the stem cell pool as the ultimate source of tissue maintenance. Regeneration is the goal of expanding and activating this reserve.
Mechanism
Regeneration is often achieved by modulating the local stem cell niche and providing specific growth factors or peptide signals that promote quiescence exit and symmetrical division. Hormones and peptides, such as Growth Hormone and specific Thymosin fractions, can directly influence the proliferation and differentiation pathways of various stem cell types. By enhancing the signaling environment, the stem cell pool is stimulated to replenish its numbers and improve its differentiation fidelity, thereby supporting systemic tissue repair and organ function.
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